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糖尿病视网膜病变

什么是糖尿病视网膜病变?

糖尿病视网膜病变是糖尿病患者因并发症引发的病症,当高血糖水平损害眼球后部或视网膜时便会发生。若未及时诊断和治疗,可能导致失明,因此糖尿病患者必须提高对此病的警惕。该病症影响80%患病20年及以上的糖尿病患者,且患者患病时间越长,罹患糖尿病视网膜病变的风险就越高。

gettext.alts.diabetic_retinopathy_what_is

糖尿病视网膜病变的成因是什么?

糖尿病视网膜病变是指糖尿病患者因高血糖水平导致视网膜(即眼球后部对光敏感的组织)受损的病症。视网膜需要持续的血液供应才能将光线转化为电信号,这些信号随后传至大脑进行图像处理,从而实现视觉功能。供血依赖于微血管网络,而持续高血糖会损伤该网络,这一过程分为三个阶段:

第一阶段:

血管内会形成小肿块,可能出现轻微出血,但通常不会影响视力。这种情况称为背景性视网膜病变。

第二阶段:

血管发生更显著的变化,包括更严重的出血,称为增殖前期视网膜病变。

第三阶段:

视网膜上会形成瘢痕组织和新生血管,这些血管脆弱且易出血,这种病变称为增殖性视网膜病变,可能导致部分视力丧失。

然而,若能及早发现该病症,通过改变生活方式及其他治疗手段可防止病情恶化。

同时需警惕与糖尿病视网膜病变高风险相关的因素,例如:

  • 患糖尿病时间较长;长期存在高血糖

压或高胆固醇
  • ;怀孕
期间

以及具有

亚洲或非洲加勒比血统
  • 。该病症影响1型和2型糖尿病患者,常伴随视网膜血管病变。
  • 若长期存在高血糖、高血压或高胆固醇问题。
  • 若处于妊娠期。
  • 若具有亚洲或非洲-加勒比血统。

该病症影响I型和II型糖尿病患者,且通常无早期预警征兆。值得庆幸的是,糖尿病视网膜病变需数年时间才会发展到威胁视力的阶段,且存在多种降低风险的方法。糖尿病患者务必做到:•

  • 按全科医生和验光师建议定期接受眼部筛查•
  • 按医嘱服用降糖药物•
  • 严格控制血糖、血压及胆固醇水平•
  • 视力出现任何变化时立即联系验光师•
  • 通过均衡饮食、规律运动及戒烟维持健康生活方式

糖尿病

视网膜病变

的症状

通常糖尿病视网膜病变的早期阶段没有明显症状,因此定期进行眼科筛查至关重要。若出现以下任何更严重的症状,请立即联系您的全科医生或验光师进行检查:

  • 视力逐渐恶化
  • 突然视力丧失 眼部
疼痛
  • 视物模糊或视野缺损
  • 视野中出现漂浮物(飞蚊症)

糖尿病眼部筛查

gettext.alts.diabetic_screening

建议所有12岁以上糖尿病患者每年进行一次眼部筛查。这些筛查至关重要,因为如前所述,糖尿病视网膜病变在早期阶段往往没有任何症状。定期眼部筛查可让验光师扫描眼底(视网膜)以发现任何病变迹象,并在必要时及早治疗。早期发现意味着患者可能避免视力丧失或减轻病情严重程度。

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Treatment of Diabetic Retinopathy

Specific treatment is not typically used until the more advanced stages of diabetic retinopathy and your vision is at risk. At all stages controlling your diabetes is vital and plays a large part in mitigating the condition. Managing your diabetes in the early stages can help prevent or reduce the damage to your eyesight and in the later stages can reduce the extent of vision loss.

For advanced diabetic retinopathy that is threatening the patient’s sight treatment includes:

  • Laser treatment
  • Eye injections
  • Eye surgery
 

Laser treatment

Laser treatment is used to treat the growth of new blood vessels in the back of the eye as they tend to be weak and often bleed into the eye. This treatment will not usually improve the patient’s sight but it can help to stabilize the changes in the eye and stop the patient’s vision getting any worse.

Treatment is done under a local anaesthetic to numb the eyes with eye drops to dilate the pupil and special contact lenses to hold the eye open and focus the laser onto the retina. The procedure usually takes around 20-40 minutes and doesn’t usually require an overnight stay in hospital. You may need to return for subsequent treatment at a laser clinic as required.

Treatment can have some side effects for a few hours such as sensitivity to light, blurred vision and aching or discomfort. These issues should be easy to manage with some self-care at home such as painkillers, wearing sunglasses and resting until you feel better.

There are some risks associated with laser treatment such as:

  • Bleeding into the eye
  • Floating objects in your field of vision (floaters)
  • A small permanent blind spot close to the centre of your vision
  • Loss of night or peripheral (side) vision which may stop you driving
  • You may be able to see the pattern left by the laser on the back of your eye for a few months.
 

Eye injections

In some cases eye injections of anti-VEGF directly into your eyes may be used to prevent new blood vessels from forming in the retina. The main medicines used are called ranibizumab (Lucentis) and aflibercept (Eylea) and they can help improve vision or stop the condition getting worse.

The treatment is given under local anaesthetic so the eye is numb and the injection is given through a very fine needle directly into the eye ball. They are usually given once a month to begin with but will be less frequent or stopped once the patient’s vision begins to stabilise. Alternatively if the anti-VEGF medications do not work steroid mediations may be used instead.

There are some risks associated with eye injections including:

  • Watery, dry or itchy eyes
  • Eye discomfort or irritation
  • Bleeding inside the eye
  • Floating objects in your field of vision (floaters)

There is also a small risk of the injections causing a blood clot which may lead to a stroke or heart attack. This risk is small but it is important to be aware of it before undergoing treatment.

 

Eye surgery

Surgery (known as vitreoretinal surgery) may be used to remove some of the transparent jelly-like substance that fills the space behind the lens of the eye (vitreous humour). This operation is known as vitreoretinal surgery and may be necessary if there is a significant amount of blood collected in your eye or if there is a lot of scar tissue which may cause or has already caused retinal detachment.

The surgery is carried out under local anaesthetic and sedation meaning the patient is unconscious during the surgery and does not experience any pain. During the procedure the surgeon makes a small incision and removes some of the vitreous humour and any scar tissue before using a laser to prevent any further loss of vision.

Potential risks of this surgery include:

  • Retinal detachment
  • Further bleeding in the eye
  • Infection in the eye
  • Fluid build-up in the cornea
  • Developing a cataract

若糖尿病视网膜病变未及时治疗的风险

若糖尿病视网膜病变未及时治疗,视网膜血管将遭受严重损伤,患者将出现视力丧失,最终导致失明。

gettext.alts.diabetic_risks

糖尿病视网膜病变常见问题解答